Manufactured by:ProteoGenix
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Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb – Research Grade

Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb – Research Grade from ProteoGenix; catalogue PX-TA2131; research use only.

SKU:
ABM133934-1
Manufacturer SKU
PX-TA2131
Product type
Primary Antibodies
TargetOpelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb – Research Grade
ApplicationsELISA
Expression systemXtenCHO
Purity>95% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction to Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb is a highly specific monoclonal antibody that targets the Mast/stem cell growth factor receptor Kit (KIT) protein. This biosimilar is a research grade product that has been developed to mimic the structure and function of the original KIT antibody, making it a valuable tool for scientific research.

Structure of Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb is a recombinant monoclonal antibody produced in a mammalian cell expression system. It is composed of two identical heavy chains and two identical light chains, each with a molecular weight of approximately 50 kDa. The antibody has a Y-shaped structure with two antigen-binding sites, allowing it to bind to the KIT protein with high specificity.

Activity of Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb The primary function of Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb is to bind to the KIT protein and inhibit its activity. KIT is a receptor tyrosine kinase that is involved in cell growth, proliferation, and survival. Dysregulation of KIT has been linked to various diseases, including cancer. By binding to KIT, Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb blocks its signaling pathway and prevents the growth and survival of cells expressing high levels of KIT.

Application of Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb has a wide range of applications in scientific research. It can be used as a tool to study the role of KIT in various cellular processes and to investigate its involvement in disease development. In cancer research, Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb can be used to study the effects of KIT inhibition on tumor growth and to identify potential therapeutic targets for KIT-driven cancers.

Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb can also be used in drug discovery and development. As KIT is a known therapeutic target, this biosimilar can be used to screen for potential KIT inhibitors and to evaluate their efficacy in preclinical studies. Its high specificity and ability to block KIT signaling make it a valuable tool in the development of targeted cancer therapies.

In addition, Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb can be used in diagnostic assays to detect the expression levels of KIT in patient samples. This can aid in the diagnosis and monitoring of KIT-driven diseases, as well as in predicting the response to KIT-targeted therapies.

Conclusion

Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb is a highly specific monoclonal antibody that targets the KIT protein. Its structure and activity make it a valuable tool for scientific research, particularly in the fields of cancer research and drug development. With its wide range of applications, this biosimilar has the potential to advance our understanding of KIT and its role in disease, as well as to aid in the development of targeted therapies for KIT-driven diseases.

ProteoGenix catalogue number PX-TA2131. For research use only.

Target: Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Monoclonal
Isotype
IgG1, kappa
Source organism
Human
Sequence
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
Technical note
For research use only. Not suitable for human use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Opelkibart Biosimilar – Anti-Mast/stem cell growth factor receptor Kit mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2131
UniProt accession
P10721
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£155.00£124.00