Manufactured by:ProteoGenix
Save 20%RUO

Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade

Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade from ProteoGenix; catalogue PX-TA2197; research use only.

SKU:
ABM133854-1
Manufacturer SKU
PX-TA2197
Product type
Primary Antibodies
TargetLinclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade
Expression systemXtenCHO
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction

Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade is a therapeutic antibody that targets the MEGT1;CD3e protein. This biosimilar is designed to mimic the activity of the original therapeutic antibody, providing a more affordable and accessible treatment option for patients.

Structure of Linclatamig Biosimilar

Linclatamig Biosimilar is a monoclonal antibody, meaning it is derived from a single type of immune cell. It is composed of two identical heavy chains and two identical light chains, which are connected by disulfide bonds. The antibody has a Y-shaped structure, with the two arms of the Y binding to the MEGT1;CD3e protein.

Activity of Linclatamig Biosimilar

The main activity of Linclatamig Biosimilar is to bind to the MEGT1;CD3e protein on the surface of immune cells. This binding triggers a signaling cascade that activates the immune cells, leading to their proliferation and activation. This activation of immune cells is crucial for fighting off infections and diseases.

In addition to its direct activity on immune cells, Linclatamig Biosimilar also has an indirect activity through its ability to bind to the Fc receptors on other cells. This binding can trigger immune responses in these cells, further enhancing the body’s defense mechanisms.

Application of Linclatamig Biosimilar

The main application of Linclatamig Biosimilar is in the treatment of diseases that involve dysregulated immune responses, such as autoimmune diseases and certain types of cancer. By targeting the MEGT1;CD3e protein, this biosimilar can help to regulate and enhance the immune response, leading to improved outcomes for patients.

Some specific diseases that Linclatamig Biosimilar may be used to treat include rheumatoid arthritis, multiple sclerosis, and certain types of leukemia. It may also be used in combination with other therapies to enhance their effectiveness.

Research Grade

Linclatamig Biosimilar is classified as a research grade therapeutic antibody, meaning it is primarily used for research purposes rather than clinical use. This allows scientists and researchers to study its structure, activity, and potential applications in a controlled laboratory setting.

However, as more research and clinical trials are conducted, Linclatamig Biosimilar may eventually be approved for clinical use and become a valuable treatment option for patients.

Conclusion

In summary, Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade is a therapeutic antibody that targets the MEGT1;CD3e protein. Its structure, activity, and application make it a promising candidate for the treatment of various diseases involving dysregulated immune responses. As further research and clinical trials are conducted, this biosimilar may become an important tool in the fight against these diseases.

ProteoGenix catalogue number PX-TA2197. For research use only.

Target: Linclatamig Biosimilar – Anti-MEGT1;CD3e mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-MEGT1, G6D, Megakaryocyte-enhanced gene transcript 1 protein, NG25, LY6G6D, C6orf23, Protein Ly6-D, Lymphocyte antigen 6 complex locus protein G6d, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Clonality
Monoclonal
Isotype
IgG1, kappa
Source organism
Human
Sequence
MKPQFVGILLSSLLGAALGNRMRCYNCGGSPSSSCKEAVTTCGEGRPQPGLEQIKLPGNPPVTLIHQHPACVAAHHCNQVETESVGDVTYPAHRDCYLGDLCNSAVASHVAPAGILAAAATALTCLLPGLWSG
Technical note
For research use only. Not suitable for human use.
Identifiers & database references
Manufacturer SKU
PX-TA2197
UniProt accession
O95868 & P07766
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£145.00£116.00