Manufactured by:ProteoGenix
Save 20%RUO

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb – Research Grade

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb – Research Grade from ProteoGenix; catalogue PX-TA1953; research use only.

SKU:
ABM134108-1
Manufacturer SKU
PX-TA1953
Product type
Primary Antibodies
TargetLafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Title: Understanding the Structure and Activity of Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb for Therapeutic Targeting

Introduction:

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb is a promising therapeutic antibody that has been developed for targeting the envelope glycoprotein gp160 of the human immunodeficiency virus (HIV). In this article, we will explore the structure, activity, and potential applications of this biosimilar in the field of HIV research.

Structure:

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb is a monoclonal antibody (mAb) that is derived from a hybridoma cell line. It is a recombinant antibody, meaning it is produced through genetic engineering techniques. The antibody consists of two identical heavy chains and two identical light chains, which are connected by disulfide bonds. These chains together form the characteristic Y-shaped structure of an antibody.

The variable regions of the antibody, also known as the antigen-binding sites, are responsible for recognizing and binding to the envelope glycoprotein gp160 of HIV. These regions are highly specific and have been engineered to have a high affinity for the gp160 protein. The constant regions of the antibody, on the other hand, are responsible for activating the immune system and promoting the destruction of the target.

Activity:

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb exerts its activity by binding to the envelope glycoprotein gp160 of HIV. This protein is essential for the virus to enter and infect human cells. By targeting this protein, the antibody prevents the virus from attaching to and entering the host cells, thereby inhibiting its replication and spread.

Furthermore, the binding of the antibody to the gp160 protein also triggers an immune response. This leads to the activation of immune cells, such as natural killer cells and macrophages, which can recognize and destroy HIV-infected cells. This dual mechanism of action makes Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb a potent therapeutic agent for targeting HIV.

Application:

The primary application of Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb is in the treatment of HIV infection. It can be used as a standalone therapy or in combination with other antiretroviral drugs. The biosimilar has shown promising results in preclinical studies, with the potential to reduce viral load and prevent disease progression.

In addition to its therapeutic use, Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb also has potential applications in HIV research. It can be used as a tool for studying the structure and function of the envelope glycoprotein gp160, as well as for investigating the mechanisms of HIV infection and immune response.

Conclusion:

Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb is a novel therapeutic antibody that holds great promise in the field of HIV research. Its specific structure and dual mechanism of action make it a potent agent for targeting the envelope glycoprotein gp160 of HIV. As further studies and clinical trials are conducted, this biosimilar has the potential to become a valuable addition to the current arsenal of HIV treatments.

ProteoGenix catalogue number PX-TA1953. For research use only.

Target: Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env, Human Immunodeficiency Virus (HIV)
Clonality
Monoclonal
Isotype
IgG1-kappa
Source organism
CAS: 2743342-91-6
Sequence
MRVTEIRKSYQHWWRWGIMLLGILMICNAEEKLWVTVYYGVPVWKEATTTLFCASDRKAYDTEVHNVWATHACVPTDPNPQEVELKNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNGNDTNTTSSSRGMVGGGEMKNCSFNITTNIRGKVQKEYALFYKLDIAPIDNNSNNRYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGKGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSANFADNAKVIIVQLNESVEINCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNLSRAKWNDTLNKIVIKLREQFGNKTIVFKHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNVTEESNNTVENNTITLPCRIKQIINMWQEVGRAMYAPPIRGQIRCSSNITGLLLTRDGGPEDNKTEVFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGAVFLGFLGAAGSTMGAAAMTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTAVPWNASWSNKSLNKIWDNMTWIEWDREINNYTSIIYSLIEESQNQQEKNEQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFSVLSIVNRVRQGYSPLSFQTHLPSSRGPDRPGGIEEEGGERDRDRSGPLVNGFLALIWVDLRSLFLFSYHRLRDLLLIVMRIVELLGLAGGWEVLKYWWNLLQYWSQELKNSAVSLLNATAVAVAEGTDRVIEVLQRAVRAILHIPRRIRQGLERALL
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Lafuvitug Biosimilar – Anti-Envelope glycoprotein gp160 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1953
UniProt accession
Q03805
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£149.00£119.20