Manufactured by:ProteoGenix
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Hnk20Mab Biosimilar – Anti-RSV glycoprotein F mAb – Research Grade

Hnk20Mab Biosimilar – Anti-RSV glycoprotein F mAb – Research Grade from ProteoGenix; catalogue PX-TA1083; research use only.

SKU:
ABM134951-1
Manufacturer SKU
PX-TA1083
Product type
Primary Antibodies
TargetHnk20Mab Biosimilar – Anti-RSV glycoprotein F mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Hnk20Mab Biosimilar is a research grade antibody that targets the respiratory syncytial virus (RSV) glycoprotein F. This monoclonal antibody (mAb) has been developed as a potential therapeutic for RSV infection, which is a major cause of respiratory illness in infants and young children. In this article, we will discuss the structure, activity, and potential applications of Hnk20Mab Biosimilar in the field of RSV research.

Structure of Hnk20Mab Biosimilar

Hnk20Mab Biosimilar is a humanized IgG1 monoclonal antibody that specifically binds to the fusion protein of RSV, glycoprotein F. It is composed of two heavy chains and two light chains, each containing a variable region and a constant region. The variable region of the antibody is responsible for its specificity and binds to a specific epitope on the RSV glycoprotein F. The constant region is responsible for the effector functions of the antibody, such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).

Activity of Hnk20Mab Biosimilar

Hnk20Mab Biosimilar has been shown to effectively neutralize RSV infection in vitro by blocking the fusion of the virus with the host cell. This prevents the virus from entering and replicating in the cells, thus reducing the viral load and preventing the spread of infection. In addition, Hnk20Mab Biosimilar has also been shown to enhance the clearance of RSV-infected cells by activating the immune system through ADCC and CDC mechanisms. This results in the elimination of infected cells and further reduces the viral load.

Applications of Hnk20Mab Biosimilar

The primary application of Hnk20Mab Biosimilar is in the treatment of RSV infection. It can be used as a therapeutic agent in patients with severe RSV infection, especially in high-risk populations such as infants and young children. Hnk20Mab Biosimilar can also be used as a prophylactic treatment to prevent RSV infection in high-risk individuals, such as premature infants and immunocompromised patients.

In addition to its therapeutic applications, Hnk20Mab Biosimilar can also be used as a research tool in the field of RSV. It can be used to study the mechanism of RSV infection and the role of glycoprotein F in the viral life cycle. Hnk20Mab Biosimilar can also be used in diagnostic assays to detect the presence of RSV in patient samples.

Conclusion

Hnk20Mab Biosimilar is a promising antibody that specifically targets the RSV glycoprotein F and has shown potential in the treatment and prevention of RSV infection. Its unique structure and activity make it an effective therapeutic and research tool in the field of RSV. Further studies and clinical trials are needed to fully evaluate the potential of Hnk20Mab Biosimilar in the treatment of RSV infection and its potential use in other respiratory diseases.

ProteoGenix catalogue number PX-TA1083. For research use only.

Target: Hnk20Mab Biosimilar – Anti-RSV glycoprotein F mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
Hnk20Mab,HNK20,RSV glycoprotein F,anti-RSV glycoprotein F
Clonality
Monoclonal
Isotype
IgA-nd
Source organism
Mouse
Sequence
MELLILKANAITTILTAVTFCFASGQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPPTNNRARRELPRFMNYTLNNAKKTNVTLSKKRKRRFLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEINLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGMDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTTNIMITTIIIVIIVILLSLIAVGLLLYCKARSTPVTLSKDQLSGINNIAFSN
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Hnk20Mab Biosimilar – Anti-RSV glycoprotein F mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1083
UniProt accession
P03420
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20