Manufactured by:ProteoGenix
Save 20%RUO

Gocatamig Biosimilar – Anti-DLL3;CD3e;ALB mAb – Research Grade

Gocatamig Biosimilar – Anti-DLL3;CD3e;ALB mAb – Research Grade from ProteoGenix; catalogue PX-TA2192; research use only.

SKU:
ABM133858-1
Manufacturer SKU
PX-TA2192
Product type
Primary Antibodies
TargetGocatamig Biosimilar – Anti-DLL3;CD3e;ALB mAb – Research Grade
Expression systemXtenCHO
Purity>95% by SDS-PAGE

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction

Gocatamig Biosimilar is a therapeutic antibody that targets three key proteins: DLL3, CD3e, and ALB. This biosimilar is a research grade antibody that has been designed to mimic the activity of the original Gocatamig antibody, providing researchers with a more cost-effective option for their studies. In this article, we will discuss the structure, activity, and application of Gocatamig Biosimilar in detail.

Structure of Gocatamig Biosimilar

Gocatamig Biosimilar is a monoclonal antibody, meaning it is produced from a single type of immune cell. It is composed of two heavy chains and two light chains, which are connected by disulfide bonds. The heavy chains are made up of constant and variable regions, while the light chains only have variable regions. The variable regions are responsible for binding to the target proteins, while the constant regions determine the antibody’s effector functions.

Activity of Gocatamig Biosimilar

Gocatamig Biosimilar targets three proteins: DLL3, CD3e, and ALB. DLL3 is a transmembrane protein that is overexpressed in certain types of cancer, including small-cell lung cancer. By targeting DLL3, Gocatamig Biosimilar can potentially inhibit the growth and proliferation of cancer cells. CD3e is a protein found on the surface of T cells, and by binding to it, Gocatamig Biosimilar can activate T cells and enhance their ability to kill cancer cells. ALB is a protein found in the blood that is involved in regulating the immune response. By targeting ALB, Gocatamig Biosimilar can potentially modulate the immune response and enhance the body’s ability to fight cancer.

Application of Gocatamig Biosimilar

Gocatamig Biosimilar is primarily used in research studies to investigate the role of DLL3, CD3e, and ALB in cancer. By targeting these proteins, researchers can gain a better understanding of their function and potential as therapeutic targets. Gocatamig Biosimilar can also be used in preclinical studies to evaluate its efficacy and safety as a potential cancer treatment. Additionally, Gocatamig Biosimilar can be used in diagnostic assays to detect the presence of DLL3, CD3e, and ALB in patient samples, providing valuable information for cancer diagnosis and treatment.

Therapeutic Antibody

Gocatamig Biosimilar is a therapeutic antibody, meaning it is designed to specifically target and treat a disease. Antibodies are a type of protein produced by the immune system to recognize and neutralize foreign substances, such as bacteria and viruses. Therapeutic antibodies, like Gocatamig Biosimilar, are engineered to target specific proteins involved in disease processes, making them a highly targeted and effective treatment option.

Therapeutic Target: DLL3, CD3e, and ALB

The three proteins targeted by Gocatamig Biosimilar – DLL3, CD3e, and ALB – are all involved in cancer. DLL3 is overexpressed in small-cell lung cancer, making it a potential therapeutic target for this type of cancer. CD3e is involved in T cell activation, and enhancing T cell activity can be beneficial in cancer treatment. ALB is involved in regulating the immune response, and targeting it can potentially enhance the body’s ability to fight cancer. By targeting these proteins, Gocatamig Biosimilar has the potential to be an effective therapeutic option for cancer treatment.

Conclusion

Gocatamig Biosimilar is a research grade therapeutic antibody that targets three key proteins involved in cancer: DLL3, CD3e, and ALB. Its structure, activity, and application make it a valuable tool for researchers studying these proteins and their potential as therapeutic targets. With its potential to inhibit

ProteoGenix catalogue number PX-TA2192. For research use only.

Target: Gocatamig Biosimilar – Anti-DLL3;CD3e;ALB mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE; Buffer: 0.01M PBS, pH 7.4.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
anti-Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, ALB, Albumin
Clonality
Monoclonal
Isotype
Ig single chain scFvhl-VH-VH'
Source organism
Human
Sequence
MVSPRMSGLLSQTVILALIFLPQTRPAGVFELQIHSFGPGPGPGAPRSPCSARLPCRLFFRVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRDAWPGTFSFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEPPAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCLEGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQPCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALGFGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRRGHSQDAGSRLLAGTPEPSVHALPDALNNLRTQEGSGDGPSSSVDWNRPEDVDPQGIYVISAPSIYAREVATPLFPPLHTGRAGQRQHLLFPYPSSILSVK
Technical note
For research use only. Not suitable for human use.
Identifiers & database references
Manufacturer SKU
PX-TA2192
UniProt accession
Q9NYJ7 & P07766 & P02768
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£155.00£124.00