Evinacumab Biosimilar – Anti-ANGPTL3 mAb – Research Grade from ProteoGenix; catalogue PX-TA1369; research use only.
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Evinacumab is a recombinant human IgG4 monoclonal antibody targeting human angiopoietin-like protein 3 (ANGPTL3). The ANGPTL protein family has many physiological functions-including the regulation of lipid metabolism. It has been noted that the loss-of-function mutation of ANGPTL3 leads to hypolipidemia and subsequently reduces cardiovascular risk, while increased function seems to be related to cardiovascular risk. Evinacumab has been used to treat homozygous familial hypercholesterolemia (HoFH). It has been sold under the Evkeeza brand name.
ProteoGenix catalogue number PX-TA1369. For research use only.
Target: Evinacumab Biosimilar – Anti-ANGPTL3 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Evinacumab Biosimilar – Anti-ANGPTL3 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
