Erzotabart Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade from ProteoGenix; catalogue PX-TA1945; research use only.
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Erzotabart Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade is a novel biosimilar antibody that has shown promising results in targeting the therapeutic protein, Cyclic ADP-ribose hydrolase 1 (CD38). This antibody has the potential to revolutionize the treatment of various diseases, including cancer and autoimmune disorders. In this article, we will discuss the structure, activity, and potential applications of Erzotabart Biosimilar in detail.
Erzotabart Biosimilar is a monoclonal antibody (mAb) that is produced by recombinant DNA technology. It is a biosimilar of the original antibody, which means it has a highly similar structure and function to the original antibody. The mAb consists of two identical heavy chains and two identical light chains, which are connected by disulfide bonds. The heavy chains contain a constant region and a variable region, while the light chains only have a variable region. The variable regions of the antibody are responsible for binding to the target protein, CD38.
The main activity of Erzotabart Biosimilar is to target and bind to CD38, a protein that is overexpressed in various diseases. CD38 is a multifunctional enzyme that is involved in the regulation of calcium signaling and cell proliferation. It is also a marker for certain types of cancer cells and has been linked to the development of autoimmune disorders. By binding to CD38, Erzotabart Biosimilar inhibits its activity and disrupts its function, leading to a decrease in calcium signaling and cell proliferation.
Erzotabart Biosimilar has shown promising results in pre-clinical studies and has the potential to be used in various therapeutic applications. The main application of this biosimilar is in the treatment of cancer, particularly multiple myeloma, a type of blood cancer. CD38 is highly expressed on the surface of multiple myeloma cells, making it an ideal therapeutic target for Erzotabart Biosimilar. By inhibiting CD38, this biosimilar can induce cell death and slow down the progression of the disease.
In addition to cancer, Erzotabart Biosimilar may also have potential applications in autoimmune disorders such as rheumatoid arthritis, lupus, and multiple sclerosis. CD38 has been implicated in the development of these diseases, and by targeting it, Erzotabart Biosimilar can potentially modulate the immune response and reduce inflammation.
In conclusion, Erzotabart Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade is a promising biosimilar antibody that has the potential to target and inhibit the activity of CD38, a protein that is involved in various diseases. Its unique structure and mechanism of action make it a potential game-changer in the treatment of cancer and autoimmune disorders. Further clinical trials are needed to fully evaluate the efficacy and safety of this biosimilar, but the initial results are promising.
ProteoGenix catalogue number PX-TA1945. For research use only.
Target: Erzotabart Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Buffer: 0.01M PBS, pH 7.4; Applications: ELISA, WB.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA |
|---|---|---|---|---|---|---|---|---|
| Erzotabart Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
