Manufactured by:ProteoGenix
Save 20%RUO

Bapotulimab Biosimilar – Anti-ILDR2 mAb – Research Grade

Bapotulimab Biosimilar – Anti-ILDR2 mAb – Research Grade from ProteoGenix; catalogue PX-TA1645; research use only.

SKU:
ABM134403-1
Manufacturer SKU
PX-TA1645
Product type
Primary Antibodies
TargetBapotulimab Biosimilar – Anti-ILDR2 mAb – Research Grade
ApplicationsELISA, WB
Expression systemXtenCHO
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Introduction

Bapotulimab Biosimilar, also known as Anti-ILDR2 mAb, is a monoclonal antibody that has been developed as a biosimilar to the original drug, Bapotulimab. This biosimilar is designed to target the ILDR2 protein, which is a therapeutic target for various diseases. In this article, we will discuss the structure, activity, and potential applications of Bapotulimab Biosimilar, highlighting its potential as a research-grade antibody.

Structure of Bapotulimab Biosimilar

Bapotulimab Biosimilar is a monoclonal antibody, which means it is made up of identical immune cells that are clones of a single parent cell. This type of antibody is designed to specifically bind to a particular target, in this case, the ILDR2 protein. The structure of Bapotulimab Biosimilar is similar to the original drug, Bapotulimab, as it is a biosimilar. It consists of two heavy chains and two light chains, which are linked together by disulfide bonds. The heavy chains are made up of four constant regions and one variable region, while the light chains have two constant regions and one variable region. The variable regions are responsible for binding to the target, while the constant regions provide stability and effector functions.

Activity of Bapotulimab Biosimilar

Bapotulimab Biosimilar is a potent inhibitor of the ILDR2 protein. ILDR2 is a transmembrane protein that is expressed in various tissues, including the brain, heart, and liver. It is involved in cell adhesion and plays a crucial role in maintaining the integrity of tissues. However, overexpression of ILDR2 has been linked to various diseases, including cancer and autoimmune disorders. Bapotulimab Biosimilar works by binding to ILDR2 and blocking its activity, thereby inhibiting disease progression. This antibody has shown promising results in preclinical studies, demonstrating its potential as a therapeutic agent.

Application of Bapotulimab Biosimilar

Bapotulimab Biosimilar has the potential to be used in various applications, particularly in the field of research. As a biosimilar, it can serve as a more cost-effective alternative to the original drug, Bapotulimab, for researchers studying the ILDR2 protein. This antibody can be used in in vitro and in vivo studies to further understand the role of ILDR2 in disease and to develop potential treatments. Furthermore, Bapotulimab Biosimilar can also be used as a diagnostic tool to detect the expression of ILDR2 in tissues, providing valuable information for disease diagnosis and prognosis.

Future Directions

Bapotulimab Biosimilar is currently in the preclinical stage of development, with promising results from in vitro and in vivo studies. However, further research is needed to fully understand its potential as a therapeutic agent. Clinical trials will be necessary to evaluate the safety and efficacy of this biosimilar in humans. If successful, Bapotulimab Biosimilar has the potential to become a valuable treatment option for diseases associated with ILDR2 overexpression.

Conclusion

In summary, Bapotulimab Biosimilar is a monoclonal antibody that targets the ILDR2 protein, which is involved in various diseases. Its structure is similar to the original drug, Bapotulimab, and it works by inhibiting the activity of ILDR2. This biosimilar has the potential to be used in research as a cost-effective alternative to the original drug. Further studies are needed to fully understand its potential as a therapeutic agent. Bapotulimab Biosimilar holds promise as a research-grade antibody and may have future applications in disease diagnosis and treatment.

ProteoGenix catalogue number PX-TA1645. For research use only.

Target: Bapotulimab Biosimilar – Anti-ILDR2 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Bapotulimab,BAY-1905254, IMMUNOGLOBULIN G2 (DE-446-LYSINE), ANTI-(HUMAN IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING RECEPTOR 2) (HUMAN MONOCLONAL BAY 1905254 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL BAY 1905254 .KAPPA.-CHAIN, DIMER IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS ILDR2 (IMMUNOGLOBULIN LIKE DOMAIN CONTAINING RECEPTOR 2, C1ORF32)), HOMO SAPIENSMONOCLONAL ANTIBODY (BAPOTULIMAB),ILDR2,anti-ILDR3
Clonality
Monoclonal
Isotype
IgG2,Kappa
Source organism
CAS 2359413-58-2
Sequence
MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKSYCQDRMGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Bapotulimab Biosimilar – Anti-ILDR2 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1645
UniProt accession
Q71H61
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20