Manufactured by:ProteoGenix
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Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade

Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade from ProteoGenix; catalogue PX-TA1180; research use only.

SKU:
ABM134862-1
Manufacturer SKU
PX-TA1180
Product type
Primary Antibodies
TargetBapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade
ApplicationsELISA, WB
Expression systemMammalian cells
Purity>85%

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction to Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade is a monoclonal antibody that has been developed as a potential treatment for Alzheimer’s disease. This biosimilar is designed to target amyloid-beta (Abeta) protein, which is believed to play a crucial role in the development and progression of Alzheimer’s disease. In this article, we will provide a detailed description of the structure, activity, and potential applications of Bapineuzumab Biosimilar.

Structure of Bapineuzumab Biosimilar

Bapineuzumab Biosimilar is a monoclonal antibody that is produced by recombinant DNA technology. It is a humanized antibody, meaning that it is derived from non-human sources but has been modified to resemble a human antibody. The antibody is composed of two identical heavy chains and two identical light chains, which are linked together by disulfide bonds. The heavy and light chains contain variable regions that are responsible for binding to the target protein, Abeta.

Activity of Bapineuzumab Biosimilar

Bapineuzumab Biosimilar works by binding to and neutralizing Abeta protein, which is known to form toxic plaques in the brains of Alzheimer’s patients. These plaques are believed to contribute to the cognitive decline and memory loss associated with the disease. By targeting and binding to Abeta, Bapineuzumab Biosimilar prevents the formation of these plaques and may slow down the progression of Alzheimer’s disease.

In addition to targeting Abeta, Bapineuzumab Biosimilar also has an immunomodulatory effect. It has been shown to activate the immune system and stimulate the production of anti-inflammatory cytokines, which may help to reduce inflammation in the brain. This is important as chronic inflammation has been linked to the development of Alzheimer’s disease.

Potential Applications of Bapineuzumab Biosimilar

Bapineuzumab Biosimilar is currently being investigated as a potential treatment for Alzheimer’s disease. It is believed that by targeting Abeta, this biosimilar may slow down the progression of the disease and improve cognitive function in patients. Clinical trials have shown promising results, with some patients showing improvements in cognitive function and a reduction in the size of Abeta plaques.

Aside from its potential as a therapeutic treatment, Bapineuzumab Biosimilar also has potential applications in research. It can be used as a tool to study the role of Abeta in Alzheimer’s disease and to better understand the mechanisms of action of this biosimilar. Additionally, Bapineuzumab Biosimilar can be used to develop diagnostic tests for early detection of Alzheimer’s disease.

Conclusion

In conclusion, Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade is a monoclonal antibody that has been developed as a potential treatment for Alzheimer’s disease. It works by targeting and neutralizing Abeta protein, which is believed to play a crucial role in the development and progression of the disease. This biosimilar has shown promising results in clinical trials and also has potential applications in research. With further studies and development, Bapineuzumab Biosimilar may offer a new treatment option for Alzheimer’s disease and contribute to a better understanding of this debilitating condition.

ProteoGenix catalogue number PX-TA1180. For research use only.

Target: Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: Mammalian cells; Purity: >85%; Buffer: PBS buffer PH7.5; Applications: ELISA, WB.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Download the manufacturer safety data sheet (MSDS/SDS)

Key facts & specifications
Also known as
Bapineuzumab,AAB-001,APP Abeta,anti-APP Abeta
Clonality
Monoclonal
Isotype
IgG1-nd
Source organism
CAS 648895-38-9
Sequence
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN
Technical note
For research use only. Not suitable for clinical or therapeutic use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Bapineuzumab Biosimilar – Anti-APP Abeta mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA1180
UniProt accession
P05067
Storage, stability & shipping
Storage conditions
store at -80°C
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20