Anti-TDO2 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22424; research use only.
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Anti-TDO2 Polyclonal Antibody: A Powerful Tool for Studying Tryptophan Metabolism in Biotech Research
Tryptophan is an essential amino acid that plays a crucial role in various biological processes, including protein synthesis and neurotransmitter production. However, excessive levels of tryptophan can lead to the production of toxic metabolites, which can have detrimental effects on the body. This is where the Anti-TDO2 Polyclonal Antibody comes in – a highly specific and sensitive tool for studying tryptophan metabolism in biotech research.
The Anti-TDO2 Polyclonal Antibody targets the enzyme Tryptophan 2,3-dioxygenase 2 (TDO2), which is responsible for the conversion of tryptophan to kynurenine. This antibody binds to TDO2 with high affinity, inhibiting its activity and allowing for the accurate measurement of tryptophan levels in biological samples.
This antibody is a valuable tool for researchers studying tryptophan metabolism and its effects on various diseases, including cancer, autoimmune disorders, and neurological disorders. It can also be used to investigate the role of TDO2 in immune tolerance and inflammation.
1. Measurement of Tryptophan Levels: The Anti-TDO2 Polyclonal Antibody can be used in ELISA or Western blot assays to measure tryptophan levels in biological samples, providing valuable insights into the regulation of tryptophan metabolism in different conditions.
2. Inhibition of TDO2 Activity: By binding to TDO2, this antibody can inhibit its activity and prevent the production of toxic metabolites. This is particularly useful in cancer research, where TDO2 is overexpressed and contributes to tumor growth.
3. Identification of TDO2 Interacting Proteins: The Anti-TDO2 Polyclonal Antibody can be used in co-immunoprecipitation experiments to identify proteins that interact with TDO2, providing a better understanding of its role in various biological processes.
Conclusion:
The Anti-TDO2 Polyclonal Antibody is a powerful tool for studying tryptophan metabolism in biotech research. Its high specificity and sensitivity make it an ideal choice for accurately measuring tryptophan levels and inhibiting TDO2 activity. With its various applications and experimental use cases, this antibody is a must-have for any researcher looking to gain a deeper understanding of tryptophan metabolism and its implications in disease. Order now and take your biotech research to the next level.
ProteoGenix catalogue number ARO-A22424. For research use only.
Target: Tryptophan 23-dioxygenase, TDO, EC:1.13.11.11, Tryptamin 23-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase, TDO2, TDO; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Tryptophan 23-dioxygenase, TDO, EC |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
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Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.