Manufactured by:ProteoGenix
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Anti-Human GRP78/HSPA5 Antibody (huMAb159)

Anti-Human GRP78/HSPA5 Antibody (huMAb159) from ProteoGenix; catalogue ARO-A23058; research use only.

SKU:
ABM121055-1
Manufacturer SKU
ARO-A23058
Product type
Primary Antibodies
Target78 kDa glucose-regulated protein, BiP, Binding-immunoglobulin protein, EC:3.6.4.10, Endoplasmic reticulum chaperone BiP, GRP-78, GRP78, HSP70 family protein 5, HSPA5, Heat shock protein 70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein
ApplicationsELISA, IHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Anti-Human GRP78/HSPA5 Antibody (huMAb159)

Biological Function

The Anti-Human GRP78/HSPA5 Antibody (huMAb159) is a highly specific and sensitive antibody that targets the glucose-regulated protein 78 (GRP78) or heat shock protein 5 (HSPA5). GRP78/HSPA5 is a key chaperone protein that plays a crucial role in protein folding, assembly, and transport within the cell. It is also known to regulate cell signaling and survival pathways, making it an important protein in various cellular processes.

Main Applications

This antibody is primarily used in research studies to detect and quantify GRP78/HSPA5 expression levels in various biological samples. It is also widely used in immunohistochemistry (IHC) and immunofluorescence (IF) assays to visualize the localization of GRP78/HSPA5 within cells and tissues. Additionally, it can be used in western blotting and flow cytometry experiments to analyze protein-protein interactions and protein expression profiles.

Experimental Use Cases

The Anti-Human GRP78/HSPA5 Antibody (huMAb159) has been successfully used in several experimental settings, including cancer research, neurodegenerative diseases, and viral infections. In cancer research, this antibody has been used to study the role of GRP78/HSPA5 in tumor growth, metastasis, and drug resistance. In neurodegenerative diseases, it has been used to investigate the involvement of GRP78/HSPA5 in protein misfolding and aggregation. Furthermore, this antibody has been used to study the interaction between GRP78/HSPA5 and viral proteins in viral infections, providing valuable insights into virus-host interactions.

In summary, the Anti-Human GRP78/HSPA5 Antibody (huMAb159) is a powerful tool for researchers to study the biological function of GRP78/HSPA5 and its role in various cellular processes. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its successful use in various experimental settings demonstrates its reliability and versatility. Order now and advance your research with this top-quality antibody.

Research Target Keywords: GRP78, HSPA5, glucose-regulated protein 78, heat shock protein 5, chaperone protein, protein folding, protein assembly, protein transport, cell signaling, cell survival, immunohistochemistry, immunofluorescence, western blotting, flow cytometry, cancer research, neurodegenerative diseases, viral infections, tumor growth, metastasis, drug resistance, protein misfolding, protein aggregation, virus-host interactions.

ProteoGenix catalogue number ARO-A23058. For research use only.

Target: 78 kDa glucose-regulated protein, BiP, Binding-immunoglobulin protein, EC:3.6.4.10, Endoplasmic reticulum chaperone BiP, GRP-78, GRP78, HSP70 family protein 5, HSPA5, Heat shock protein 70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein; Clonality: Monoclonal Antibody; Reactivity: Human; Applications: ELISA, IHC.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Also known as
Anti-78 kDa glucose-regulated protein, BiP, Binding-immunoglobulin protein, EC:3.6.4.10, Endoplasmic reticulum chaperone BiP, GRP-78, GRP78, HSP70 family protein 5, HSPA5, Heat shock protein 70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein
Clonality
Monoclonal
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

SpeciesWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISAIHC
Human
Identifiers & database references
Manufacturer SKU
ARO-A23058
Storage, stability & shipping
Storage conditions
4°C for short term (1 week), store at -20°C to -80°C for long term(1 year); Avoid repeated freeze-thaw cycles
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£239.00£191.20