Anti-Human CD59 Polyclonal Antibody from ProteoGenix; catalogue ARO-A22048; research use only.
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Anti-Human CD59 Polyclonal Antibody: A Versatile Tool for Immunology Research
Anti-Human CD59 Polyclonal Antibody is a highly specific and reliable tool for immunology research. This polyclonal antibody is designed to target the CD59 protein, also known as protectin, which is a cell surface glycoprotein involved in the regulation of complement-mediated cell lysis. With its wide range of applications and proven experimental use cases, this antibody is a valuable addition to any biotech laboratory.
CD59 is a key regulator of the complement system, a crucial part of the immune response that helps defend the body against pathogens. This protein works by inhibiting the formation of the membrane attack complex (MAC), a structure that can cause cell lysis. By binding to CD59, this antibody can block the action of the MAC and prevent cell damage, making it an important tool for studying the immune response.
The Anti-Human CD59 Polyclonal Antibody has a wide range of applications in immunology research. It can be used in various techniques such as flow cytometry, immunohistochemistry, and Western blotting to detect and quantify CD59 expression in different cell types and tissues. This antibody is also suitable for functional studies, as it can inhibit the activity of CD59 and study its role in the complement system.
This polyclonal antibody has been extensively used in research on various diseases, including autoimmune disorders, infectious diseases, and cancer. In a study published in the Journal of Immunology, researchers used this antibody to investigate the role of CD59 in autoimmune kidney disease. Another study published in the Journal of Virology used this antibody to study the role of CD59 in HIV infection. These examples demonstrate the versatility and reliability of this antibody in different research areas.
This polyclonal antibody is specifically designed for research use and is not intended for diagnostic or therapeutic purposes. It is produced in a host animal and purified using advanced techniques to ensure high specificity and sensitivity. With its high affinity and low background, this antibody is an ideal choice for studying CD59 in various research applications.
ProteoGenix catalogue number ARO-A22048. For research use only.
Target: CD59 glycoprotein; 1F5 antigen; 20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59; CD59; MIC11; MIN1; MIN2; MIN3; MSK21; Clonality: Polyclonal Antibody; Reactivity: Human; Applications: ELISA, IHC.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
