Manufactured by:ProteoGenix
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Alextatug Biosimilar – Anti-PABP-1 mAb – Research Grade

Alextatug Biosimilar – Anti-PABP-1 mAb – Research Grade from ProteoGenix; catalogue PX-TA2108; research use only.

SKU:
ABM133955-1
Manufacturer SKU
PX-TA2108
Product type
Primary Antibodies
TargetAlextatug Biosimilar – Anti-PABP-1 mAb – Research Grade
ApplicationsELISA
Expression systemXtenCHO
Purity>95% by SDS-PAGE.

Manufacturer provenance

Manufactured by:
ProteoGenix
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Introduction

Alextatug Biosimilar – Anti-PABP-1 mAb is a research grade monoclonal antibody that has shown promising results in targeting PABP-1, a key protein involved in various cellular processes. This biosimilar antibody has the potential to be a valuable tool in research and has potential therapeutic applications. In this article, we will discuss the structure, activity, and potential applications of Alextatug Biosimilar – Anti-PABP-1 mAb.

Structure of Alextatug Biosimilar – Anti-PABP-1 mAb

Alextatug Biosimilar – Anti-PABP-1 mAb is a monoclonal antibody, which means it is produced by a single clone of immune cells. This antibody is a biosimilar, which is a biological product that is highly similar to an already approved biological product. The structure of this biosimilar antibody is designed to mimic the structure of the original antibody, making it highly specific and effective in its activity.

The antibody is composed of two heavy chains and two light chains, with each chain consisting of variable and constant regions. The variable regions are responsible for binding to the target protein, while the constant regions provide stability and facilitate interactions with other immune cells. The heavy and light chains are connected by disulfide bonds, giving the antibody its characteristic Y-shaped structure.

Activity of Alextatug Biosimilar – Anti-PABP-1 mAb

The primary target of Alextatug Biosimilar – Anti-PABP-1 mAb is PABP-1, a protein involved in the regulation of gene expression, cell proliferation, and cell survival. PABP-1 is overexpressed in many types of cancer and has been linked to tumor growth and metastasis. By binding to PABP-1, Alextatug Biosimilar – Anti-PABP-1 mAb can inhibit its activity and disrupt the signaling pathways involved in cancer progression.

In addition to its anti-

cancer activity, Alextatug Biosimilar – Anti-PABP-1 mAb has also shown potential in regulating immune responses. PABP-1 has been found to play a role in the activation and proliferation of immune cells, and by targeting this protein, Alextatug Biosimilar – Anti-PABP-1 mAb can modulate immune responses and potentially treat autoimmune diseases.

Applications of Alextatug Biosimilar – Anti-PABP-1 mAb

1.

Cancer Research: The overexpression of PABP-1 in various types of cancer makes it an attractive therapeutic target. Alextatug Biosimilar – Anti-PABP-1 mAb can be used as a research tool to study the role of PABP-1 in cancer progression and as a potential treatment option for cancer.

2. Drug Development: The ability of Alextatug Biosimilar – Anti-PABP-1 mAb to target PABP-1 makes it a promising candidate for the development of new cancer therapies. This biosimilar antibody can be used in combination with other drugs to enhance their effectiveness and reduce the risk of drug resistance.

3. Autoimmune Diseases: PABP-1 has been implicated in the development of autoimmune diseases, and Alextatug Biosimilar – Anti-PABP-1 mAb has the potential to modulate immune responses and treat these conditions. Further research is needed to explore the therapeutic potential of this biosimilar antibody in autoimmune diseases.

4. Biomarker Detection: PABP-1 has been identified as a potential biomarker for various types of cancer. Alextatug Biosimilar – Anti-PABP-1 mAb can be used in diagnostic tests to detect the presence of PABP-1 in patient samples, aiding in early detection and monitoring of cancer progression.

Conclusion

Alextatug Biosimilar – Anti-PABP-1 mAb is a research grade monoclonal antibody that has shown promising results in targeting PABP-1, a key protein involved in cancer and immune responses. Its specific structure and activity make it a valuable tool in cancer research and a potential therapeutic agent for cancer and autoimmune diseases.

ProteoGenix catalogue number PX-TA2108. For research use only.

Target: Alextatug Biosimilar – Anti-PABP-1 mAb – Research Grade; Clonality: Monoclonal Antibody; Expression system: XtenCHO; Purity: >95% by SDS-PAGE.; Buffer: 0.01M PBS, pH 7.4.; Applications: ELISA.

Available configurations: 50ug, 100ug, 1mg.

Download the manufacturer datasheet

Key facts & specifications
Clonality
Monoclonal
Isotype
IgG1-lambda7
Source organism
Human
Sequence
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
Technical note
For research use only. Not suitable for human use.
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation

Evidence status by application and model.

TargetWBIHC-PIHC-FrIF/ICCFlow CytIPChIPELISA
Alextatug Biosimilar – Anti-PABP-1 mAb – Research Grade
Identifiers & database references
Manufacturer SKU
PX-TA2108
UniProt accession
P11940
Storage, stability & shipping
Storage conditions
4°C for short term; -20°C for long term
Shipped at
Blue ice (+4°C)
Compliance & documents
ISO certifications
ISO 9001:2023, ISO 14001: 2023
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

ProteoGenix
£139.00£111.20