Beclin-1 Rabbit pAb from ELK Biotechnology
Know who made it. See the evidence. Buy through one marketplace.
Beclin-1 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying Beclin-1 in WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions. One of the proteins critical to this process is Beclin-1.
| Validation evidence captions | Western blot analysis of 1) Jurkat, 2)A431 with Beclin-1 Rabbit pAb EA240 diluted at 1:2,000. |
|---|
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Species | WB | IHC | IF | ELISA | IP | FCM | ChIP |
|---|---|---|---|---|---|---|---|
| Human |
This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
BECN1 (beclin 1; Beclin-1/ATG6) is a core autophagy regulator and class III PI3K-complex component linking PI3P production to autophagosome initiation and membrane trafficking.
Biological function: Beclin-1 acts as a core subunit of class III phosphatidylinositol 3-kinase complexes that generate PI3P. Distinct BECN1-containing complexes support autophagosome initiation, autophagosome maturation and endocytic trafficking, making BECN1 central to macroautophagy and membrane-remodelling pathways.
