Manufactured by:ELK Biotechnology
RUO

MeCP2 Rabbit pAb

MeCP2 Rabbit pAb from ELK Biotechnology

SKU:
ABM101993
Manufacturer SKU
EA020
Product type
Primary Antibodies
TargetMeCP2
ApplicationsWB
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
ELK Biotechnology
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

MeCP2 Rabbit pAb is a research-use antibody from ELK Biotechnology for studying MeCP2 in WB workflows with listed reactivity for Human. Specifications and supporting documents below should be reviewed when planning the experiment.

Background

Methyl-CpG-binding protein 2(MeCP2), whose exact function is unclear. It appears to help regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein usually regulates genes involved in brain function, even though this protein is found throughout the body.Within the brain, the MeCP2 protein is important for the function of nerve cells (neurons) and is present in high levels in mature neurons. This protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. Many of the genes that are known to be regulated by the MeCP2 protein play a role in normal brain function, particularly the maintenance of synapses.

Additional antibody information

Validation evidence captions Western blot analysis of Hela with MeCP2 Rabbit pAb diluted at 1, 1:2,000 2, 1:5,000
Key facts & specifications
Research areas
Antibody Research
Also known as
Methyl CpG Binding Protein 2 ;RTS; AUTSX3; MRX16; MRX79; PPMX; RTT; Rett Syndrome; Mental Retardation,X-linked 16
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB 1:2,000
Immunogen
Synthetic Peptide
Observed band
53kDa
Cellular localization
Nucleus
Assay type
Antibody validation/application
Source organism
Rabbit
Concentration
1mg/mL
Working concentration
WB 1:2,000
Form / buffer
Liquid
Quantity per pack
50µL/100µL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIFELISAIPFCMChIP
Human
Identifiers & database references
Manufacturer SKU
EA020
UniProt entry
P51608
Storage, stability & shipping
Storage conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Long-term storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Storage warning
Avoid repeated freeze-thaw cycles.
Compliance & documents
CE marked
No
ISO certifications
ISO 9001
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by ELK Biotechnology and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MECP2methyl-CpG binding protein 2

View target guide

MECP2 identifies methyl-CpG binding protein 2 in Homo sapiens (Human). This target record connects NCBI Gene 4204, UniProtKB P51608 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4204
UniProtKB
P51608
ELK Biotechnology
£176.00