Manufactured by:Boster Bio
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Anti-MEK2/MAP2K2 Antibody Picoband® (monoclonal, 2B4

Primary Antibody supplied by Boster Bio

SKU:
ABM23637-1
Manufacturer SKU
M00996-2
Product type
Primary Antibodies
TargetDual specificity mitogen-activated protein kinase kinase 2
ApplicationsELISA, Flow Cytometry, IF/ICC, IHC, IHC-P, WB
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
Boster Bio
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Anti-MEK2/MAP2K2 Antibody Picoband® (monoclonal, 2B4 is a research-use antibody from Boster Bio for studying Dual specificity mitogen-activated protein kinase kinase 2 in ELISA, Flow Cytometry, IF/ICC, IHC, IHC-P, WB workflows with listed reactivity for Human, Mouse, Rat. Specifications and supporting documents below should be reviewed when planning the experiment.

Boster Bio Anti-MEK2/MAP2K2 Antibody Picoband® (monoclonal, 2B4) catalog # M00996-2. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2), also called PRKMK2 or MEK2, is an enzyme that in humans is encoded by the MAP2K2 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K2 is mapped to 19p13.3. This kinase is known to play a critical role in mitogen growth factor signal transduction, and the inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax. Recombinant MEK2 and MEK1 both could activate human ERK1 in vitro, and they further characterized biochemically the 2 MAP2Ks. MAP2K2 has been shown to interact with MAPK3 and ARAF.

Product information

Key facts & specifications
Also known as
ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; MAP2K2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; MKK2; PRKMK2
Host species
Mouse
Clonality
Monoclonal
Clone number
Clone: 2B4
Isotype
Mouse IgG2b
Cross-reactivity
No cross-reactivity with other proteins.
Dilution range
Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x106 cells, Human
Immunogen
E.coli-derived human MEK2/MAP2K2 recombinant protein (Position: M1-V400).
Observed band
45 kDa
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Purification
Immunogen affinity purified.
Form / buffer
Lyophilized
Sequence fragment
E.coli-derived human MEK2/MAP2K2 recombinant protein (Position: M1-V400).
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesWBIHCIHC-PIHC-FIF/ICCFlow CytometryELISAIP
Human
Mouse
Rat
Identifiers & database references
Manufacturer SKU
M00996-2
Gene symbol
MAP2K2
Gene ID
5605
UniProt accession
P36507
Storage, stability & shipping
Shelf life
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage conditions
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Shipped at
Ambient or cold-chain dependent on product format
Short-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Long-term storage
Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.
Storage buffer
Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.
Storage warning
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Compliance & documents
CE marked
No
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Boster Bio and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MAP2K2mitogen-activated protein kinase kinase 2

View target guide

MAP2K2 identifies mitogen-activated protein kinase kinase 2 in Homo sapiens (Human). This target record connects NCBI Gene 5605, UniProtKB P36507 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
5605
UniProtKB
P36507
Boster Bio
£328.00£278.80