Human A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1, ADAMTS1 ELISA Kit
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Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | Serum | Plasma | Cell culture supernatants | Ascites | Tissue homogenates |
|---|---|---|---|---|---|
| Compatibility |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
ADAM metallopeptidase with thrombospondin type 1 motif 1 (ADAMTS1/ADAMTS-1), also known as METH-1, is a secreted extracellular metalloprotease. This ABMIUM guide connects its verified identity to catalogue-backed research products and authoritative NCBI/UniProt evidence.
Biological function: ADAMTS1 is a secreted metalloprotease of the ADAMTS family. Reviewed UniProt reports cleavage of extracellular-matrix substrates including aggrecan and cartilage oligomeric matrix protein (COMP), together with anti-angiogenic activity and a proposed role in follicular rupture.
