beta-Actin Monoclonal Antibody
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Beta-actin (PS1TP5-binding protein 1), also known as ACTB, PS1TP5BP1. Entrez Protein NP_001092. It is one of six different actin proteins. Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton.Actins are highly conserved proteins that are involved in various types of cell motility, structure, and integrity. Actin is ubiquitously expressed in all eukaryotic cells. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
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This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Actin beta (ACTB) encodes actin, cytoplasmic 1, commonly called beta-actin or β-actin, a widely expressed non-muscle cytoskeletal actin. Human ACTB maps to NCBI Gene 60 and reviewed UniProtKB P60709; this target record links the verified target to related ABMIUM catalogue products.
Biological function: ACTB is a highly conserved actin that polymerises from monomeric G-actin into F-actin filaments and cross-linked cytoskeletal networks. NCBI and reviewed UniProt describe roles in cell structure, motility and contraction; nuclear G- and F-actin also contribute to transcriptional regulation and repair of damaged DNA.
