Manufactured by:BT LAB
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MMP1 Monoclonal Antibody

MMP1 Monoclonal Antibody

SKU:
ABM204501
Manufacturer SKU
BT-MCA3825
Product type
Primary Antibodies
TargetMMP1
ApplicationsWB, IHC-P, IF/ICC, Flow Cytometry, ELISA, IHC
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Key facts & specifications
Research areas
Cardiovascular
Also known as
CLG;CLGN
Host species
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Dilution range
WB: 1:500 - 1:2000; IHC-p: 1:200 - 1:1000; ICC: 1:200 - 1:1000; FCM: 1:200 - 1:400; ELISA: 1:10000
Immunogen
Purified recombinant fragment of human MMP1 expressed in E. Coli.
Molecular weight
54kDa
Quantity per pack
100μL, 50μL
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pICCFCMELISAIHC
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA3825
Gene ID
4312
UniProt accession
P08253
Storage, stability & shipping
Storage conditions
Store at 4°C short term. Aliquot and store at -20°C long term.
Short-term storage
Store at 4°C short term.
Long-term storage
Aliquot and store at -20°C long term.
Storage buffer
Ascitic fluid containing 0.03% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MMP1matrix metallopeptidase 1

View target guide

Matrix metallopeptidase 1 (MMP1), also known as interstitial collagenase or collagenase-1, is a secreted zinc-dependent matrix metalloproteinase involved in extracellular-matrix turnover. ABMIUM catalogue products linked below support research on MMP1 biology.

Biological function: Matrix metallopeptidase 1 (MMP1/interstitial collagenase) is a secreted zinc-dependent endopeptidase that cleaves fibrillar collagens and other extracellular-matrix substrates. By contributing to collagen breakdown and matrix remodelling, MMP1 participates in normal tissue turnover and is widely studied in repair, inflammation, fibrosis and tumour-stroma biology.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4312
UniProtKB
P03956
BT LAB
£240.93£205.00