Manufactured by:BT LAB
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CD4 Monoclonal Antibody

CD4 Monoclonal Antibody

SKU:
ABM199143
Manufacturer SKU
BT-MCA0302
Product type
Primary Antibodies
TargetCD4
ApplicationsELISA, Flow Cytometry
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Key facts & specifications
Research areas
Immunology, Stem Cells
Also known as
CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4; Leu-3; CD antigen CD4
Host species
Mouse
Clonality
Monoclonal
Isotype
IgG
Dilution range
ELISA: 1:10000; FC: 1:200 - 1:400
Immunogen
Purified recombinant fragment of human CD4 expressed in E. Coli.
Concentration
1 mg/ml
Purification
Affinity purification
Quantity per pack
50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceELISAFCFCM
Applications
Identifiers & database references
Manufacturer SKU
BT-MCA0302
Gene ID
920
UniProt accession
P01730
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Purified antibody in PBS containing 0.03% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CD4CD4 molecule

View target guide

CD4 identifies CD4 molecule in Homo sapiens (Human). This target record connects NCBI Gene 920, UniProtKB P01730 and related ABMIUM catalogue products.

Biological function: CD4 is a cell-surface glycoprotein expressed on helper T cells and additional immune-cell subsets. It acts as a coreceptor for MHC class II during antigen recognition and supports T-cell receptor signalling.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
920
UniProtKB
P01730
BT LAB
£135.52£115.00