Manufactured by:BT LAB
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Trk B(Phospho Tyr516) Polyclonal Antibody

Trk B(Phospho Tyr516) Polyclonal Antibody

SKU:
ABM196550
Manufacturer SKU
BT-AP15159
Product type
Primary Antibodies
TargetNTRK2
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

Key facts & specifications
Research areas
Cancer, Metabolism, Neuroscience, Cell Biology, Developmental Biology, Signal Transduction
Also known as
BDNF/NT-3 growth factors receptor; NTRK2; TRKB; BDNF/NT-3 growth factors receptor; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk B around the phosphorylation site of Tyr515. AA range:481-530
Molecular weight
91999
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP15159
Gene ID
4915
UniProt accession
Q16620
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

NTRK2neurotrophic receptor tyrosine kinase 2

View target guide

NTRK2 identifies neurotrophic receptor tyrosine kinase 2 in Homo sapiens (Human). This target record connects NCBI Gene 4915, UniProtKB Q16620 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
4915
UniProtKB
Q16620
BT LAB
£81.31£69.00