Manufactured by:BT LAB
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SRPK2 Polyclonal Antibody

SRPK2 Polyclonal Antibody

SKU:
ABM194618
Manufacturer SKU
BT-AP14483
Product type
Primary Antibodies
TargetSRPK2
ApplicationsWB, ELISA
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Ser-52 and Ser-588.,Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.,sequence The cDNA appears to contain a duplicated region.,Belongs to the protein kinase superfamily.,Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.,Contains 1 protein kinase domain.,tissue specificity:Highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.,

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling, Cell Biology
Also known as
SRSF protein kinase 2 ;EC 2.7.11.1;SFRS protein kinase 2;Serine/arginine-rich protein-specific kinase 2;SR-protein-specific kinase 2 [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protei
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 5000 - 1: 20000
Immunogen
Synthesized peptide derived from part region of human protein
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
100ul, 50ul, 20ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP14483
Gene ID
6733
UniProt accession
P78362
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

BT LAB
£207.05£176.00