Manufactured by:BT LAB
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Parathyroid hormone/parathyroid hormone-related peptide Receptor Polyclonal Antibody

Parathyroid hormone/parathyroid hormone-related peptide Receptor Polyclonal Antibody

SKU:
ABM189692
Manufacturer SKU
BT-AP12786
Product type
Primary Antibodies
TargetPTH1R
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Rat, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

Know who made it. See the evidence. Buy through one marketplace.

Product description

Background

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

Key facts & specifications
Research areas
Neuroscience, Signal Transduction
Also known as
Parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 500 - 1: 200; ELISA: 1: 20000; ELISA: 1: 10000 - 1: 20000
Immunogen
Synthetic peptide from human protein at AA range: 46-122
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP12786
Gene ID
5745
UniProt accession
Q03431
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

PTH1Rparathyroid hormone 1 receptor

View target guide

PTH1R identifies parathyroid hormone 1 receptor in Homo sapiens (Human). This target record connects NCBI Gene 5745, UniProtKB Q03431 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
5745
UniProtKB
Q03431
BT LAB
£81.31£69.00