Manufactured by:BT LAB
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EST1 Rabbit Polyclonal Antibody

EST1 Rabbit Polyclonal Antibody

SKU:
ABM180662
Manufacturer SKU
BT-AP09762
Product type
Primary Antibodies
TargetCES1
ApplicationsWB
Species / reactivityHuman, Mouse

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Key facts & specifications
Research areas
Cardiovascular, Metabolism, Signal Transduction
Also known as
EST1; Liver carboxylesterase 1; Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1; CE-1; hCE-1; EC 3.1.1.1; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; EC 3.1.1.56; Monocyte/macrophage serine esterase; Retinyl ester hydrolase; REH; Serine esterase 1; Triacylglycerol hydrolase; TGH)
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000
Immunogen
Synthesized peptide derived from human EST1
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWB
Applications
Identifiers & database references
Manufacturer SKU
BT-AP09762
Gene ID
1066
UniProt accession
P23141
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.142% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

CES1carboxylesterase 1

View target guide

CES1 identifies carboxylesterase 1 in Homo sapiens (Human). This target record connects NCBI Gene 1066, UniProtKB P23141 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
1066
UniProtKB
P23141
BT LAB
£81.00£69.00