pNO40 Polyclonal Antibody
Know who made it. See the evidence. Buy through one marketplace.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Evidence | IHC | ELISA | IHC-p |
|---|---|---|---|
| Applications |
This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
