Manufactured by:BT LAB
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c-Src(Phospho Tyr419) Polyclonal Antibody

c-Src(Phospho Tyr419) Polyclonal Antibody

SKU:
ABM172282
Manufacturer SKU
BT-AP06923
Product type
Primary Antibodies
TargetSRC
ApplicationsWB, IHC-P, ELISA, IF/ICC
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling, Cancer, Signal Transduction
Also known as
Proto-oncogene tyrosine-protein kinase Src; SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC-p: 1: 100 - 1: 300; ELISA: 1: 20000
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human c-Src (phospho Tyr419)
Molecular weight
59704
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHC-pELISAIF
Applications
Identifiers & database references
Manufacturer SKU
BT-AP06923
Gene ID
6714
UniProt accession
P12931
Storage, stability & shipping
Shelf life
-20°C for 1 year
Storage conditions
-20°C for 1 year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

SRCSRC proto-oncogene, non-receptor tyrosine kinase

View target guide

SRC identifies SRC proto-oncogene, non-receptor tyrosine kinase in Homo sapiens (Human). This target record connects NCBI Gene 6714, UniProtKB P12931 and related ABMIUM catalogue products.

Organism
Homo sapiens (Human)
NCBI Gene
6714
UniProtKB
P12931
BT LAB
£81.00£69.00