Manufactured by:BT LAB
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Histone H4 (Acetyl Lys8) Polyclonal Antibody

Histone H4 (Acetyl Lys8) Polyclonal Antibody

SKU:
ABM163990
Manufacturer SKU
BT-AP04105
Product type
Primary Antibodies
TargetHIST1H4A
ApplicationsWB, IHC, IF/ICC, ELISA, IHC-P
Species / reactivityHuman, Mouse, Rat, Monkey

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST4H4 is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from HIST4H4 lack polyA tails; instead, they contain a palindromic termination element.

Key facts & specifications
Research areas
Epigenetics and Nuclear Signaling
Also known as
HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HI
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC: 1: 100 - 1: 300; IF: 1: 200 - 1: 1000; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human Histone H4 around the acetylated site of Lys8. AA range:1-50
Molecular weight
11367
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHCIFELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP04105
UniProt accession
P62805
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

H4C1Histone H4

View target guide

H4C1 is associated with Histone H4 in Homo sapiens (Human). This target record connects UniProtKB P62805 with related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
UniProtKB
P62805
BT LAB
£81.00£69.00