CEP55 Polyclonal Antibody
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CEP55 (Centrosomal protein of 55 kDa), also known as URCC6 (Up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
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This product is manufactured by BT LAB and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
