Manufactured by:BT LAB
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BST-1 Polyclonal Antibody

BST-1 Polyclonal Antibody

SKU:
ABM154683
Manufacturer SKU
BT-AP00993
Product type
Primary Antibodies
TargetBST1
ApplicationsWB, ELISA
Species / reactivityHuman

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Key facts & specifications
Research areas
Immunology
Also known as
BST1; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD157
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; ELISA: 1: 20000
Immunogen
Synthesized peptide derived from ADP-ribosyl cyclase 2 at AA range: 211-260
Molecular weight
35724
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBELISA
Applications
Identifiers & database references
Manufacturer SKU
BT-AP00993
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

BST1bone marrow stromal cell antigen 1

View target guide

BST1 (bone marrow stromal cell antigen 1), also known as CD157, is a GPI-anchored ectoenzyme whose reviewed protein is ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2.

Biological function: BST1/CD157 can catalyse formation of cyclic ADP-ribose from NAD+ and hydrolyse cyclic ADP-ribose to ADP-ribose. Cyclic ADP-ribose functions as a calcium-mobilizing second messenger, while BST1 has also been implicated in supporting pre-B-cell growth in stromal-cell contexts.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
683
UniProtKB
Q10588
BT LAB
£81.00£69.00