Manufactured by:BT LAB
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AQP4 Polyclonal Antibody

AQP4 Polyclonal Antibody

SKU:
ABM153408
Manufacturer SKU
BT-AP00558
Product type
Primary Antibodies
TargetAQP4
ApplicationsWB, IHC, ELISA, IHC-P
Species / reactivityHuman, Mouse, Rat

Manufacturer provenance

Manufactured by:
BT LAB
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Background

AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein (aquaporin 4) is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Key facts & specifications
Research areas
Signal Transduction, Metabolism
Also known as
AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4
Host species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Dilution range
WB: 1: 500 - 1: 2000; IHC: 1: 100 - 1: 300; ELISA: 1: 5000
Immunogen
The antiserum was produced against synthesized peptide derived from human AQP4. AA range:204-253
Molecular weight
34830
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Quantity per pack
20ul, 50ul, 100ul
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

EvidenceWBIHCELISAIHC-p
Applications
Identifiers & database references
Manufacturer SKU
BT-AP00558
Gene ID
361
UniProt accession
P55087
Storage, stability & shipping
Shelf life
-20°C for one year
Storage conditions
-20°C for one year
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Compliance & documents
Datasheet
Open datasheet
Product manual
Open manual
Frequently asked questions
Who manufactured this product?

This product is manufactured by BT LAB and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

AQP4aquaporin 4

View target guide

AQP4 identifies aquaporin 4 in Homo sapiens (Human). This target record connects NCBI Gene 361, UniProtKB P55087 and related ABMIUM catalogue products.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
361
UniProtKB
P55087
BT LAB
£81.00£69.00