Ascorbate Peroxidase (APX) Activity Assay Kit with collaborator-tested sample matrix evidence from Elabscience.
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Ascorbate Peroxidase (APX) Activity Assay Kit from Elabscience is intended for research workflows involving APX. Review the listed specifications and supporting documents to confirm compatibility with the intended method.
This product is manufactured by Elabscience and sold through ABMIUM without relabelling.
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APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1; APE1/Ref-1) is the major human AP endonuclease and a multifunctional DNA-repair and redox regulator. It repairs abasic sites in base-excision repair and helps regulate redox-sensitive transcription-factor activity.
Biological function: APEX1 cleaves the DNA phosphodiester backbone immediately 5′ to apurinic/apyrimidinic sites generated spontaneously or during base-excision repair, creating DNA ends for downstream repair. Reviewed UniProt also supports a redox-regulatory role toward transcription factors, linking genome maintenance with oxidative-stress signalling.
