Cystine Uptake Fluorometric Assay Kit

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Manufactured by:Elabscience
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Cystine Uptake Fluorometric Assay Kit

Cystine Uptake Fluorometric Assay Kit with collaborator-tested sample matrix evidence from Elabscience.

SKU:
ABM10319
Manufacturer SKU
E-BC-F066_96T
Product type
Assay Kits

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Cystine Uptake Fluorometric Assay Kit from Elabscience is intended for research workflows. Review the listed specifications and supporting documents to confirm compatibility with the intended method.

Key facts & specifications
Research areas
Amino Acids and Proteins, Ferroptosis
Incubation temperature
This product can be stored at -20°C for 12 months with shading light.
Assay type
Assay Kits
Detection method
Fluorometric method
Technical note
Cystine is the source of the antioxidant glutathione, which plays an important role in the redox equilibrium within cells. The cystine/glutamate transporter (xCT) on the cell membrane is one of the amino acid transporters that transports extracellular cystine into the cell and intracellular glutamate into the cell in a ratio of 1:1. xCT regulates intracellular glutathione synthesis through cystine uptake and maintains cellular redox equilibrium. When the xCT activity on the cell membrane decreases, the ability of the cell to uptake cysteine may decrease, which may lead to cell ferroptosis. In recent years, the association between xCT and related diseases such as cancer, neurodegenerative diseases, and immunity has gradually become one of the research hotspots.
This kit is a convenient kit for detecting cystine uptake ability of cells by fluorescence method. Cystine analog, like cystine, can be transported into cells through xCT on the cell membrane. Cystine analog react with fluorescent probes and emit fluorescence. Therefore, the ability of cell cystine uptake can be determined by detecting the fluorescence intensity generated by cystine analog.
Identifiers & database references
Manufacturer SKU
E-BC-F066_96T
Storage, stability & shipping
Shelf life
12 months from shipping dates
Shipped at
Wet ice (2-8 degrees C)
Short-term storage
4 degrees C for up to 6 months; do not freeze pre-coated plate
Long-term storage
4 degrees C for up to 12 months
Aliquoting guidance
Lyophilised standards and detection antibody may be reconstituted and aliquoted; store reconstituted aliquots at -20 degrees C for up to 2 weeks
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Elabscience
£432.00£345.60