ABMIUM target intelligence
KIT proto-oncogene, receptor tyrosine kinase
KIT identifies KIT proto-oncogene, receptor tyrosine kinase in Homo sapiens (Human). This target record connects NCBI Gene 3815, UniProtKB P10721 and related ABMIUM catalogue products.
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Names used across publications, databases and supplier catalogues.
KIT is a cell-surface receptor tyrosine kinase for KITLG/SCF. Ligand binding activates signalling pathways that support cell survival and proliferation and contribute to haematopoiesis, stem-cell maintenance, mast-cell biology, gametogenesis and melanogenesis.
KIT is widely studied in receptor tyrosine-kinase signalling, haematopoiesis, mast cells, stem/progenitor cells and cancer models. Reagent selection should consider species, sample type, assay format, application and supporting validation.