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ABMIUM target intelligence

CASP3

caspase 3

CASP3 identifies caspase 3 in Homo sapiens (Human). This target record connects NCBI Gene 836, UniProtKB P42574 and related ABMIUM catalogue products.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene836 UniProtP42574

CASP3 products

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Research context & evidence

About CASP3

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

CASP3 is a major executioner caspase in apoptosis. After proteolytic activation by initiator caspases, it cleaves numerous cellular substrates to carry out the apoptotic programme.

Experimental context

Research context

CASP3 is studied as a central marker and effector of programmed cell death in apoptosis, stress-response and disease-model experiments.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Caspase-3CPP32CPP32BSCA-1A830040C14RikAC-3CC3CPP32-betaLiceYamamldy