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B2M

beta-2-microglobulin

Beta-2-microglobulin (B2M, beta2-m) is the non-polymorphic light-chain component of major histocompatibility complex class I molecules. ABMIUM catalogue products linked below support research on B2M biology.

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OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene567 UniProtP61769

B2M products

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Boster BioABMIUM Verified™

Anti-Nurse Shark b2m Antibody

SKU: ABM31513-1Primary Antibodies
Target
B2M
Host
Rabbit
Clonality
Polyclonal
Reactivity
Nurse shark
Applications
ELISA, Flow Cytometry, IHC, IHC-P, WB
From£353.60£416.00 Save 15%
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Research context & evidence

About B2M

Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.

Biology

Biological function

Beta-2-microglobulin (B2M/beta2-m) associates non-covalently with major histocompatibility complex class I heavy chains and is required for stable MHC class I assembly and cell-surface expression. Through this role, B2M is integral to MHC-I antigen presentation and immune recognition by CD8-positive T cells.

Experimental context

Research context

Beta-2-microglobulin (B2M/beta2-m) is widely studied in MHC class I biology, antigen presentation, adaptive immunity and circulating or tissue biomarker research. Use the catalogue filters below to review ABMIUM products associated with B2M, then confirm species, sample type, assay format, application and product-level validation before use.

Identifiers

Alternative names

Names used across publications, databases and supplier catalogues.

Beta-2-MicroglobulinB2MGAMYLD6CDABP0092HDCMA22PIMD43MHC1D4Ly-m11beta2-mQtsA-15719