ABMIUM target intelligence
ATP citrate lyase
ACLY is ATP citrate lyase, also called ATP-citrate synthase. This record links the verified human identity (NCBI Gene 47; UniProt P53396) to ABMIUM catalogue products.
Read full target overview
Research context & evidence
Target information is kept separate from product-level validation so you can review the biology and the reagent evidence independently.
ATP citrate lyase (ACLY) generates cytosolic acetyl-CoA by converting citrate and coenzyme A in an ATP-dependent reaction that also produces oxaloacetate. The acetyl-CoA supplied by ACLY supports pathways including fatty-acid and cholesterol biosynthesis.
ACLY is studied in cytosolic acetyl-CoA production, lipid and cholesterol metabolism, nutrient-responsive metabolic regulation and biosynthetic pathway control. Use the ABMIUM catalogue products associated with ATP citrate lyase to investigate ACLY biology, then confirm species, assay format, application and product-level validation before reagent selection.
Names used across publications, databases and supplier catalogues.
