ABMIUM target intelligence
angiotensin converting enzyme 2
Angiotensin-converting enzyme 2 (ACE2; also known as ACEH) is a membrane-associated metallopeptidase in the renin-angiotensin system. This target record connects human NCBI Gene 59272, reviewed UniProtKB Q9BYF1 and related ABMIUM catalogue products.
Read full target overviewABMIUM research catalogue
Loading products for ACE2…
Names used across publications, databases and supplier catalogues.
Angiotensin-converting enzyme 2 (ACE2) is a counter-regulatory carboxypeptidase of the renin-angiotensin system. It converts angiotensin I to angiotensin-(1-9) and angiotensin II to angiotensin-(1-7), helping counterbalance classical angiotensin II signalling and supporting cardiovascular homeostasis. ACE2 also functions as a cellular receptor for HCoV-NL63, SARS-CoV and SARS-CoV-2 spike proteins.
ACE2 research spans renin-angiotensin signalling, cardiovascular and renal homeostasis, peptide processing, epithelial and endothelial biology, and coronavirus entry mechanisms. ABMIUM catalogue products associated with ACE2 can support target-focused studies; species, sample type, application and product-level validation should be confirmed on the individual product page.