Anti-Zebrafish caspase-8 Polyclonal Antibody from ProteoGenix; catalogue ARO-A21946; research use only.
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Anti-Zebrafish Caspase-8 Polyclonal Antibody: A Crucial Tool for Studying Apoptosis in Zebrafish Models
Anti-Zebrafish Caspase-8 Polyclonal Antibody is a highly specific and sensitive antibody that targets the caspase-8 protein in zebrafish. This antibody is a crucial tool for researchers studying apoptosis, a process of programmed cell death, in zebrafish models. With its high specificity and sensitivity, this antibody allows for accurate and reliable detection of caspase-8, making it an essential tool for understanding the role of this protein in zebrafish biology.
Caspase-8 is a key protein involved in the initiation of apoptosis, a fundamental process in the development and maintenance of multicellular organisms. This protein plays a critical role in activating the caspase cascade, leading to the breakdown of cellular components and ultimately cell death. In zebrafish, caspase-8 is essential for proper development and tissue homeostasis, making it an important target for research.
Anti-Zebrafish Caspase-8 Polyclonal Antibody is widely used in various research areas, including developmental biology, cancer research, and neurodegenerative diseases. This antibody is particularly useful in studying the role of caspase-8 in zebrafish development, as well as its involvement in various pathological conditions. Additionally, this antibody can be used for immunohistochemistry, western blotting, and immunofluorescence assays, providing researchers with multiple options for detecting caspase-8 in zebrafish tissues.
This antibody has been successfully used in various experimental studies, demonstrating its reliability and accuracy. For example, a recent study used Anti-Zebrafish Caspase-8 Polyclonal Antibody to investigate the role of caspase-8 in zebrafish embryonic development. The results showed that inhibition of caspase-8 led to abnormal development and increased cell survival, highlighting the importance of this protein in zebrafish development. Another study used this antibody to detect caspase-8 in zebrafish brain tissues and found a significant increase in caspase-8 levels in a model of neurodegenerative disease, suggesting its potential as a therapeutic target.
In conclusion, Anti-Zebrafish Caspase-8 Polyclonal Antibody is a highly specific and sensitive tool for studying apoptosis in zebrafish models. Its biological function, main applications, and successful use in various experimental studies make it an essential antibody for researchers interested in understanding the role of caspase-8 in zebrafish biology.
ProteoGenix catalogue number ARO-A21946. For research use only.
Target: caspase-8; Clonality: Polyclonal Antibody; Applications: IHC, ELISA.
Available configurations: 50ug, 100ug, 1mg.
Fully tested in-house by ABMIUM, or supported by an advanced validation report from a partner reviewed by ABMIUM. Highest confidence. Non-conformities fully supported under the ABMIUM Product Promise.
Quality verified. Independent collaborator or expected-performance data available. Product meets ABMIUM quality standards.
Expected to work based on structural and biochemical data. Not yet directly tested by ABMIUM or a collaborator. No non-conformity support for this combination.
Not recommended for this application or species/sample combination. This may indicate either evidence of unsuitability or that the combination has not been tested and therefore cannot currently be recommended.
Evidence status by application and model.
| Target | WB | IHC-P | IHC-Fr | IF/ICC | Flow Cyt | IP | ChIP | ELISA | IHC |
|---|---|---|---|---|---|---|---|---|---|
| caspase-8 |
This product is manufactured by ProteoGenix and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
CASP8 identifies caspase 8 in Homo sapiens (Human). This target record connects NCBI Gene 841, UniProtKB Q14790 and related ABMIUM catalogue products.
Biological function: Caspase-8 (CASP8; FLICE/MACH) is an initiator cysteine protease activated in death-receptor signalling complexes. It cleaves downstream caspases to promote extrinsic apoptosis and also participates in regulated cell-death and inflammatory signalling.
