ABMIUM target intelligence

CASP8

caspase 8

CASP8 identifies caspase 8 in Homo sapiens (Human). This target record connects NCBI Gene 841, UniProtKB Q14790 and related ABMIUM catalogue products.

Read full target overview
OrganismMultiple species; representative: Homo sapiens (Human) NCBI Gene841 UniProtQ14790

ABMIUM research catalogue

Research Products

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Alternative names and identifiers

Names used across publications, databases and supplier catalogues.

Caspase-8ALPS2BCAP4FLICEMACHMCH5

Biological function

Caspase-8 (CASP8; FLICE/MACH) is an initiator cysteine protease activated in death-receptor signalling complexes. It cleaves downstream caspases to promote extrinsic apoptosis and also participates in regulated cell-death and inflammatory signalling.

Research context

Caspase-8 (CASP8/FLICE) is studied in death-receptor signalling, apoptosis, immune regulation and regulated cell death. Use the catalogue filters below to compare ABMIUM CASP8 reagents by species, application and validation, and confirm product-level suitability before use.