Manufactured by:Elabscience
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Rekombinantes humanes APE1/APE-Protein

Rekombinantes humanes APE1/APE-Protein, geliefert von Elabscience mit technischen Spezifikationen, die vom Kooperationspartner bereitgestellt wurden.

SKU:
ABM16900-1
Manufacturer SKU
PKSH032090_10ug
Product type
Rekombinante Proteine
TargetAPE1
Species / reactivityMensch
Purity> 95 %, bestimmt mittels reduzierender SDS-PAGE.

Manufacturer provenance

Manufactured by:
Elabscience
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Recombinant Human APE1/APE Protein is a research-use recombinant protein from Elabscience preparation representing APE1 supplied as Liquid. Review the expression, purity, formulation and storage specifications below before selecting it for an assay or functional workflow.

Key facts & specifications
Research areas
Cardiovascular, Epigenetics and Nuclear Signaling
Also known as
AP-Endonuklease 1, APE, APE-1REF-1, APE1, APEN, APEX, APEX-Nuklease, APEX1, APX, Apurin-/Apyrimidin-Endonuklease 1, DNA-(Apurin- oder Apyrimidin-Stelle)-Lyase, HAP1, REF1, Redox-Faktor-1
Modification
Keiner
Molecular weight
35,6 kDa
Concentration
Betreffend den Wert des Labels.
Form / buffer
Lieferung als 0,2 μm filtrierte Lösung von 10mM HEPES, 100mM KCl, 50% Glycerin, pH 7,4.
Endotoxin level
< 1,0 EU pro µg des Proteins, bestimmt mittels LAL-Methode.
Sequence
Pro2-Leu318
Validation & performance evidence
ABMIUM Validated™ ABMIUM Verified™ Expected performance Not suitable

Application validation matrix

Evidence status by application and model.

SpeciesBioaktivitätBindungZellbasiertIn vivoELISA Capture
Human
Identifiers & database references
Manufacturer SKU
PKSH032090_10ug
Gene symbol
APE1
Gene ID
328
UniProt accession
AAH02338.1
Storage, stability & shipping
Shelf life
6 Monate
Shipped at
Dieses Produkt wird als Flüssigkeit geliefert. Der Versand erfolgt gefroren mit Kühlakkus/-packs. Nach Erhalt sofort bei < - 20°C lagern.
Short-term storage
Bei unter -20 °C lagern, 6 Monate stabil. Bitte Gefrier-Tau-Zyklen minimieren.
Long-term storage
Bei < -20°C lagern, 6 Monate stabil. Bitte Gefrier-Tau-Zyklen minimieren.
Aliquoting guidance
Gesamtes Fläschchen sofort rekonstituieren. Aliquot-Stammlösung; wiederholtes Einfrieren und Auftauen vermeiden.
Compliance & documents
REACH compliant
Yes
ISO certifications
ISO 9001:2015, ISO 14001:2015, ISO 45001:2018
Datasheet
Open datasheet
Product manual
Open manual
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by Elabscience and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

APEX1apurinic/apyrimidinic endodeoxyribonuclease 1

View target guide

APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1; APE1/Ref-1) is the major human AP endonuclease and a multifunctional DNA-repair and redox regulator. It repairs abasic sites in base-excision repair and helps regulate redox-sensitive transcription-factor activity.

Biological function: APEX1 cleaves the DNA phosphodiester backbone immediately 5′ to apurinic/apyrimidinic sites generated spontaneously or during base-excision repair, creating DNA ends for downstream repair. Reviewed UniProt also supports a redox-regulatory role toward transcription factors, linking genome maintenance with oxidative-stress signalling.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
328
UniProtKB
P27695
Elabscience
£66.00£52.80