Manufactured by:TriBio Science
RUO

WS6, Stimulates pancreatic beta-cell proliferation

Stimulates pancreatic beta-cell proliferation Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures. It has been shown to induce both α- and β-cell proliferation. May lead to the development of new therapeutics for diabetes. Induces...

SKU:
ABM148958-1
Manufacturer SKU
TBI5666-25MG | TBI5666-5MG
Product type
Biochemical Inhibitors
TargetStimulates pancreatic beta-cell proliferation
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Stimulates pancreatic beta-cell proliferation

Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures. It has been shown to induce both α- and β-cell proliferation. May lead to the development of new therapeutics for diabetes. Induces adult hippocampal neurogenesis correlating with its antidepressant effect in a rat model of chronic unpredictable mild stress-induced depression. Has been used together with TTNPB and azakenpaullone, as a defined chemical cocktail to induce mouse totipotent stem cells. Cell permeable

Key facts & specifications
Also known as
4-[[6-[Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide
Molecular weight
568.60
Form / buffer
powder
Activity
Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures. It has been shown to induce both α- and β-cell proliferation. May lead to the development of new therapeutics for diabetes. Induces adult hippocampal neurogenesis correlating with its antidepressant effect in a rat model of chronic unpredictable mild stress-induced depression. Has been used together with TTNPB and azakenpaullone, as a defined chemical cocktail to induce mouse totipotent stem cells. Cell permeable.
Molecular formula
C 29 H 31 F 3 N 6 O 3
Solubility
Soluble in DMSO (30 mg/ml)
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI5666-25MG | TBI5666-5MG
CAS number
1421227-53-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£458.00