JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion. Increases survival in a mouse ALS model. Delays or prevents autoimmune type 1 diabetes in NOD mice. Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory...
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JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion. Increases survival in a mouse ALS model. Delays or prevents autoimmune type 1 diabetes in NOD mice. Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory response syndrome. Displays protective effects against myocardial ischemia and reperfusion injury in mouse models
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JAK3 identifies Janus kinase 3 in Homo sapiens (Human). This target record connects NCBI Gene 3718, UniProtKB P52333 and related ABMIUM catalogue products.
