Potent and selective inhibitor of Src family kinases Lck and Src, IC50=2 and 6 nM respectively. Also inhibits SIK, IC50=10, 22 and 60 nM for SIK 1, 2 and 3 respectively. May be used along with PD-325901 and CHIR-99021 to support self-renewal of naïve human embryonic stem cells
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Potent and selective inhibitor of Src family kinases Lck and Src, IC50=2 and 6 nM respectively. Also inhibits SIK, IC50=10, 22 and 60 nM for SIK 1, 2 and 3 respectively. May be used along with PD-325901 and CHIR-99021 to support self-renewal of naïve human embryonic stem cells
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