Semisynthetic alkaloidal anticancer agent. Induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. Inhibits normal microtubule assembly and induces aberant tubulin polymerization1. Induces apoptosis in a variety of cell lines. Inhibits autophagosome maturation. Inhibits...
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Semisynthetic alkaloidal anticancer agent. Induces cell cycle arrest at G2/M phase by inhibiting mitotic spindle formation. Inhibits normal microtubule assembly and induces aberant tubulin polymerization1. Induces apoptosis in a variety of cell lines. Inhibits autophagosome maturation. Inhibits palmitoylation of tubulin
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