Manufactured by:TriBio Science
RUO

U0126, MEK1 and MEK2 inhibitor

Highly selective inhibitor of MEK1 and MEK2 in vitro and in vivo. Unlike PD98059, which only inhibits the activation of MEK1 and MEK2, U0126 inhibits both the active and inactive forms of the MEK enzymes. Inhibition of MEK1 and MEK2 has been demonstrated to enhance the self renewal of stem cells

SKU:
ABM148904-1
Manufacturer SKU
TBI2179-25MG | TBI2179-5MG
Product type
Biochemical Inhibitors
TargetMEK1 and MEK2
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Highly selective inhibitor of MEK1 and MEK2 in vitro and in vivo. Unlike PD98059, which only inhibits the activation of MEK1 and MEK2, U0126 inhibits both the active and inactive forms of the MEK enzymes. Inhibition of MEK1 and MEK2 has been demonstrated to enhance the self renewal of stem cells

Key facts & specifications
Also known as
1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene
Molecular weight
380.49
Form / buffer
powder
Activity
Highly selective inhibitor of MEK1 and MEK2 in vitro and in vivo. Unlike PD98059, which only inhibits the activation of MEK1 and MEK2, U0126 inhibits both the active and inactive forms of the MEK enzymes. Inhibition of MEK1 and MEK2 has been demonstrated to enhance the self renewal of stem cells.
Molecular formula
C 18 H 16 N 6 S 2
Solubility
Soluble in DMSO (up to 200 mg/ml).
Technical note
Stability: ≥ 1 year.
Identifiers & database references
Manufacturer SKU
TBI2179-25MG | TBI2179-5MG
CAS number
109511-58-2
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£311.00