TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase...
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TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle
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