Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively. Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg). Induces autophagy. Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative...
Know who made it. See the evidence. Buy through one marketplace.
Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively. Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg). Induces autophagy. Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models. Downregulates NGF expression in RSC96 cells
This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.
ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.
Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.
Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.
Mechanistic target of rapamycin kinase (MTOR), commonly called mTOR, is a serine/threonine protein kinase and core component of mTOR signalling complexes. This ABMIUM record connects NCBI Gene 2475 and UniProtKB P42345 to catalogue-backed research products.
Biological function: Mechanistic target of rapamycin kinase (mTOR/MTOR) is the catalytic kinase of mTORC1 and mTORC2. These complexes integrate nutrient, energy and growth-factor signals to regulate processes including protein synthesis, cell growth, metabolism, survival and cytoskeletal organisation.
