Manufactured by:TriBio Science
RUO

Thalidomide, E3 Ubiquitin ligase inhibitor

Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic

SKU:
ABM148844-1
Manufacturer SKU
TBI1115-100MG | TBI1115-500MG
Product type
Biochemical Inhibitors
TargetE3 Ubiquitin ligase
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic

Key facts & specifications
Also known as
N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic
Molecular weight
326.82
Form / buffer
powder
Activity
Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic.
Molecular formula
C 13 H 10 N 2 O 4
Solubility
Soluble in DMSO (up to 5 mg/ml).
Technical note
Stability: ≥ 2 years.
Identifiers & database references
Manufacturer SKU
TBI1115-100MG | TBI1115-500MG
CAS number
50-35-1
Storage, stability & shipping
Storage conditions
RT
Shipped at
4°C
Long-term storage
RT
Compliance & documents
Datasheet
Open datasheet
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

TriBio Science
£82.00