A semi-synthetic ergoline derivative which acts as a partial dopamine D2 agonist and 5HT2B/2C receptor antagonist. Displays antiparkinsonian effects in MPTP-treated cynomolgus monkeys. Partial agonist at recruitment of β-arrestin2 to the D2 receptor. Ameliorates monocrotaline-induced pulmonary...
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A semi-synthetic ergoline derivative which acts as a partial dopamine D2 agonist and 5HT2B/2C receptor antagonist. Displays antiparkinsonian effects in MPTP-treated cynomolgus monkeys. Partial agonist at recruitment of β-arrestin2 to the D2 receptor. Ameliorates monocrotaline-induced pulmonary hypertension in rats
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