Manufactured by:TriBio Science
RUO

Temsirolimus, mTOR inhibitor

mTOR(mammalian target of rapamycin) inhibitor Analog of rapamycin with similar inhibition of mTOR. Inhibited human rhabdomyosarcoma xenograft growth and angiogenesis. Caused G1/S cell cycle arrest in liver cancer cells

SKU:
ABM148826-1
Manufacturer SKU
TBI3261-25MG | TBI3261-5MG
Product type
Biochemical Inhibitors
TargetmTOR
Purity>98%

Manufacturer provenance

Manufactured by:
TriBio Science
Sold by:
ABMIUM
Fulfilled from:
Manufacturer facility or confirmed fulfilment location

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Product description

mTOR(mammalian target of rapamycin) inhibitor

Analog of rapamycin with similar inhibition of mTOR. Inhibited human rhabdomyosarcoma xenograft growth and angiogenesis. Caused G1/S cell cycle arrest in liver cancer cells

Key facts & specifications
Also known as
CCI-779
Molecular weight
1030.3
Form / buffer
powder
Activity
Analog of rapamycin with similar inhibition of mTOR. Inhibited human rhabdomyosarcoma xenograft growth and angiogenesis. Caused G1/S cell cycle arrest in liver cancer cells. Procedures First dissolved in DMSO (up to 100 mg/ml) or Ethanol (100 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 1 day.
Molecular formula
C 56 H 87 NO 16
Solubility
Soluble in DMSO (up to 100 mg/ml); or Ethanol (100 mg/ml)
Technical note
Stability: ≥ 4 years.
Identifiers & database references
Manufacturer SKU
TBI3261-25MG | TBI3261-5MG
CAS number
162635-04-3
Storage, stability & shipping
Storage conditions
-20°C
Shipped at
4°C
Long-term storage
-20°C
Compliance & documents
Datasheet
Open datasheet
Safety data sheet
Open SDS
Frequently asked questions
Who manufactured this product?

This product is manufactured by TriBio Science and sold through ABMIUM without relabelling.

Can ABMIUM ship this product internationally?

ABMIUM supports global orders. Availability, shipping requirements and applicable import arrangements are confirmed before fulfilment where required.

Can I check suitability before ordering?

Yes. Send your target, sample, application and experimental conditions through ABMIUM MATCH or technical support.

Is this product for clinical use?

Unless the listing expressly states otherwise, ABMIUM products are supplied for research use only and are not for diagnostic or therapeutic use.

Research target context

MTORmechanistic target of rapamycin kinase

View target guide

Mechanistic target of rapamycin kinase (MTOR), commonly called mTOR, is a serine/threonine protein kinase and core component of mTOR signalling complexes. This ABMIUM record connects NCBI Gene 2475 and UniProtKB P42345 to catalogue-backed research products.

Biological function: Mechanistic target of rapamycin kinase (mTOR/MTOR) is the catalytic kinase of mTORC1 and mTORC2. These complexes integrate nutrient, energy and growth-factor signals to regulate processes including protein synthesis, cell growth, metabolism, survival and cytoskeletal organisation.

Organism
Multiple species; representative: Homo sapiens (Human)
NCBI Gene
2475
UniProtKB
P42345
TriBio Science
£409.00